Regenerative Medicine: Unproven or Unprovable

I'd definitely appreciate some genuine input. Does the argument that regenerative medicine injections tend to confer benefits to select populations hold weight here? It seems from what I've read and been exposed to, if you were to take 2 hypothetical case scenarios...

1) 45 year old smoker, obese, sedentary, multiple comorbid conditions, psychiatric issues (depression), likely has symptoms consistent with chronic pain

2) 45 year old who eats a nutritious diet, healthy weight, regularly active and is in fact in your office because of overuse or minor strain/sprain from triathlon training or crossfit, minimal comorbid conditions

Would stem cell/PRP treatments be a much more viable option to patient 2 while worthless for patient 1?

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Regenerative Medicine: Unproven or Unprovable