Here is the article I see quoted most often: http://ift.tt/1jO3JP5
So many problems:
1) From 1998
2) 5(!) healthy volunteers
3) 2-hr TOTAL length of "case" - 90 min then switch
4) 2LPM flows
The list goes on.
So it doesn't really apply to the cases I would tend to use it on: those long 8-hr robotic gyn/uro cases on "fluffy" patients or something equivalent. I definitely like des wakeups much more than iso. You can wake someone up with iso equally fast, but anecdotally people seem to be much sharper and alert in PACU and on the floor afterwards.
Is switching better than doing the same thing with nitrous or propofol or just using des the whole time? Probably not. A little cheaper than using straight des, but c'mon, we're talking pennies here.
Just don't NOT do it because some attending told you that there was a study saying that there was no difference, is all I'm saying. Form your own conclusions.
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Switching Volatile Mid Case
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